Top 5 Newborn Diaper Ointments: A Parent’s Guide

That first precious diaper change with your newborn is unforgettable, but what about the next hundred? Soon, you might notice that delicate skin getting red and irritated. It’s a common worry for new parents: how do you protect your baby from diaper rash when their skin is so sensitive?

Choosing the best diaper ointment feels like navigating a maze. Should you pick zinc oxide, petroleum jelly, or something all-natural? Each product promises relief, but which one actually works best for your little one without causing other issues? The sheer volume of choices can feel overwhelming, and the last thing you want is to try five different creams before finding the right one.

This guide cuts through the confusion. We will break down the essential ingredients, explain what to look for on the label, and offer clear recommendations based on real-world needs. By the end of this post, you will feel confident choosing a diaper ointment that keeps your baby comfortable and happy.

Top Diaper Ointment For Newborns Recommendations

No. 1
A+D Original Diaper Rash Ointment Prevents & Treats Diaper Rash, Moisturizing Skin Protectant with...
  • PEDIATRICIAN RECOMMENDED DIAPER RASH OINTMENT: A+D Ointment is pediatrician-recommended and contains Vitamin A and vitamin D to soothe, moisturize & protect the skin. Free of parabens, dyes and phthalates
  • PREVENT & HEAL DIAPER RASH: Unlike lotions and creams, A+D Diaper Rash Ointment forms a thick barrier to help to prevent diaper rash by helping to seal out wetness
  • RELIEVES IRRITATED SKIN: Helps relieve the discomfort of chapped, chafed, and cracked skin. Not just for babies with sore bottoms, this ointment with lanolin can also be used to treat your cracked foot, skin, and lips
  • WASH, DRY, APPLY: This gentle formula is smooth, non-greasy and spreads evenly. Wash the area with soap and water, gently pat with dry cloth, apply A+D Ointment to protect the area. FSA/HSA Eligible
No. 2
Boudreaux’s Butt Paste Max Strength Diaper Rash Cream for Baby, Ointment With Zinc Oxide, 2 oz...
  • Relieves discomfort fast: This Maximum Strength Boudreaux's Butt Paste diaper cream helps treat and prevent diaper rash, providing fast relief and instantly protecting irritated skin with first use; this product is FSA & HSA eligible in the USA
  • Powerful, protective formula: With more than 2x the rash-fighting ingredient than our Original Butt Paste Ointment, this 40% zinc oxide cream is clinically-tested, hypoallergenic and fragrance-free; this formula is free from parabens, preservatives, dyes and talc
  • Easy application: Change soiled diaper immediately, cleanse diaper area, allow to dry and apply diaper rash ointment liberally; use as needed, especially when exposed to wet diapers for a prolonged period, such as bedtime
  • Safe for use at every diaper change: Our extra strength baby rash cream is perfect for the diaper bag and the changing table; this protective diaper rash ointment is easy to take on the go, making it safe for every diaper change
No. 3
A+D Original Diaper Rash Ointment, Prevents & Protects Diaper Rash, Moisturizes & Heals Dry Skin...
  • PEDIATRICIAN RECOMMENDED DIAPER RASH OINTMENT: A+D Ointment is pediatrician-recommended and contains Vitamin A and vitamin D to soothe, moisturize & protect the skin. Free of parabens, dyes and phthalates
  • PREVENT & HEAL DIAPER RASH: Unlike lotions and creams, A+D Diaper Rash Ointment forms a thick barrier to help to prevent diaper rash by helping to seal out wetness
  • RELIEVES IRRITATED SKIN: Helps relieve the discomfort of chapped, chafed, and cracked skin. Not just for babies with sore bottoms, this ointment with lanolin can also be used to treat your cracked foot, skin, and lips
  • WASH, DRY, APPLY: This gentle formula is smooth, non-greasy and spreads evenly. Wash the area with soap and water, gently pat with dry cloth, apply A+D Ointment to protect the area. FSA/HSA Eligible
No. 4
Aquaphor Baby Healing Ointment Advanced Therapy Skin Protectant, Dry Skin and Diaper Rash Ointment,...
  • ONE ESSENTIAL SOLUTION: Aquaphor Baby Healing Ointment is clinically proven to restore smooth, healthy skin, a perfect multi-purpose solution for your baby's many skin care needs, a perfect addition to your diaper bag
  • HEALING OINTMENT FOR TENDER SKIN: Provide extra gentle care for your babys tender and delicate skin by applying
  • DIAPER RASH PREVENTION: Use Aquaphor Ointment as a preventative diaper rash ointment and apply with every diaper change to protect the skin from wetness, acidity and chafing to help avoid rashes
  • GREAT FOR PARENTS TOO: Parents can also use the dry skin ointment as a body moisturizer, to soften dry hands and cuticles, cracked heels or chapped lips
No. 5
The Honest Company Hypoallergenic Diaper Rash Cream, Moisturizing, Calming Zinc Oxide Ointment, NEA...
  • Diaper Rash - meet your match; Our clean, gentle formula glides on easily and is infused with our Soothing Phyto-Blend to help form and support a healthy, protective skin barrier to sooth irritation
  • Rapid relief zinc oxide formula helps treat diaper rash, seal out wetness, and protect chafed skin
  • Cleanse and dry your baby's rash and the affected area before applying the diaper ointment
  • NEA Recognized; Cruelty Free; Made in the USA; Hypoallergenic; Physician Tested
No. 6
Aquaphor Baby Healing Ointment Advanced Therapy Skin Protectant for Chapped or Dry Skin, Drool Rash...
  • ONE ESSENTIAL SOLUTION: Aquaphor Baby Healing Ointment restores smooth, healthy skin; a perfect multipurpose solution for your baby's many skin care needs
  • TEETHING AND DROOL RASH: Provide extra gentle care for your baby’s tender and delicate skin by applying to irritated and chapped skin from teething, drool rash and more
  • DIAPER RASH PREVENTION: Aquaphor Ointment is a preventative diaper rash ointment that protects delicate skin from wetness, acidity and chafing to help avoid rashes
  • GREAT FOR PARENTS: Parents can also use the dry skin ointment as a body moisturizer, to soften dry hands and cuticles, cracked heels or chapped lips
No. 7
Boudreaux’s Butt Paste Max Strength Diaper Rash Cream for Baby, Ointment With Zinc Oxide, 4 oz...
  • Clinically tested baby diaper rash formula helps provide fast relief from diaper rash discomfort and instantly protects irritated skin with first use
  • Thick, cream-like protective paste with 40% Zinc Oxide has over 2x the rash fighting ingredient (versus Original Butt Paste Ointment)
  • Seals out moisture for instant protection that lasts through the night and helps keep baby’s boo-tay dry
  • It's ideal for daily prevention and treatment of moderate to more irritated diaper rash
No. 8
Aquaphor Baby Healing Ointment (14 Oz) + 3-in-1 Diaper Rash Cream (3.5 Oz), Hypoallergenic and...
  • GENTLE CARE FOR BABY: Use Aquaphor Baby Healing Ointment with Petrolatum (a skin protectant) to provide extra gentle care for your baby's tender and delicate skin by applying it to dry, irritated and chapped skin from teething, drool rash and more
  • MULTIPURPOSE OINTMENT: Also use Ointment as a preventative diaper rash cream and apply with every diaper change to protect the skin from wetness, acidity and chafing to help avoid diaper rashes
  • DIAPER RASH CREAM: If the diaper area gets irritated, use Aquaphor Baby Diaper Rash Cream to soothe and treat mild to moderate diaper rash flare-ups
  • SOOTHING FORMULA: Aquaphor Baby Diaper Rash Cream is formulated with Zinc Oxide (a skin protectant) to protect baby's delicate skin and effectively treat diaper rash—preservative and fragrance free, soothing for dry, sensitive skin

The Ultimate Buying Guide for Newborn Diaper Ointments

Choosing the right diaper ointment for your newborn is a big decision. You want something that keeps your baby comfortable and prevents that painful diaper rash. This guide helps you understand what to look for so you can pick the best protection for your little one’s delicate skin.

Key Features to Look For

When shopping, keep these important features in mind. These elements tell you how well the ointment will work.

1. Barrier Protection Strength

The main job of a diaper ointment is to create a strong shield. This barrier stops wetness and poop from touching your baby’s skin directly. Look for thick, rich formulas that stay put even after a wet diaper.

2. Ease of Application and Removal

You will use this product many times a day. A good ointment spreads easily without needing a lot of rubbing. Also, check if it washes off easily during cleanup. Some very thick pastes can be hard to remove, which might irritate the baby’s skin during changes.

3. Hypoallergenic and Fragrance-Free Status

Newborn skin is very sensitive. Always choose products labeled “hypoallergenic.” This means they are less likely to cause allergic reactions. Avoid added perfumes or dyes, as these often cause irritation.

Important Ingredients and Materials

The ingredients are the most important part of the ointment. Certain materials create the best protective layer.

Primary Active Ingredients

  • Zinc Oxide: This is the gold standard. Zinc oxide works by creating a thick, white barrier. It also has mild healing properties. Look for concentrations between 10% and 40%. Higher percentages usually mean a stronger barrier.
  • Petrolatum (Petroleum Jelly): This ingredient locks moisture out. It is very effective at preventing wetness from reaching the skin. It is safe and widely used.

Soothing and Healing Additives

These extras help calm any existing redness.

  • Lanolin: Derived from wool, lanolin is a great moisturizer. It helps keep the skin soft. (Note: If your family has wool allergies, check with your pediatrician first.)
  • Shea Butter or Natural Oils: These plant-based ingredients offer gentle nourishment and soothing relief.

Factors That Improve or Reduce Quality

Not all ointments are made equally. A few quality markers can make a huge difference in performance.

Quality Indicators (Improve Quality)

Products that use minimal ingredients tend to perform better for newborns. High-quality ointments often use medical-grade zinc oxide. They focus on blocking moisture rather than masking smells.

Quality Reducers (Reduce Quality)

Avoid ointments that list many chemicals you cannot pronounce. Ingredients like parabens or harsh preservatives can dry out or irritate sensitive newborn skin. If an ointment feels watery or rubs in completely clear, it might not offer enough barrier protection.

User Experience and Use Cases

Think about how you will use the product throughout the day.

Daily Use vs. Treatment

For daily prevention, a moderate layer of a zinc oxide cream works perfectly at every diaper change. If your baby already has a bad rash, you might need a thicker, paste-like ointment with a higher zinc percentage (like 40%) to treat the area more aggressively. Always apply the treatment generously to clean, dry skin.

Application Tips

Many parents prefer ointments that come in a tub, as you can scoop out a generous amount. However, some prefer tubes for travel because they are less messy. Decide which packaging suits your routine best.


10 Frequently Asked Questions (FAQ) About Newborn Diaper Ointments

Q: When should I start using diaper ointment?

A: You should start using it right away, from the very first diaper change. Prevention is easier than treatment.

Q: How much ointment should I apply?

A: Apply a visible, thick layer—like frosting a cupcake. You should still be able to see a white layer on the skin, especially in the creases.

Q: Do I need to wipe off all the old ointment at every change?

A: If the ointment is still fully covering the skin, you only need to gently wipe away the stool and urine. If the ointment looks thin or dirty, gently clean the area before reapplying a fresh layer.

Q: Can I use adult creams like Vaseline?

A: While petroleum jelly is a good barrier, dedicated diaper ointments often contain zinc oxide, which actively heals and treats rash better than plain petroleum jelly alone.

Q: Is it okay if the ointment has a slight medicinal smell?

A: Yes. Ointments with zinc oxide often have a mild, earthy smell. This is usually better than added artificial perfumes that can irritate the baby.

Q: What is the best zinc oxide percentage for a newborn?

A: For daily prevention, 10% to 20% is usually enough. If a rash starts, switch to 30% to 40% zinc oxide.

Q: Can these ointments stain cloth diapers?

A: Yes, ointments containing a high amount of zinc oxide or petrolatum can build up on cloth diapers. If you use cloth, consider using a barrier cloth liner or switching to a more natural, thinner cream on non-rash days.

Q: How often should I reapply the ointment?

A: Reapply at every single diaper change, day and night, to maintain the protective barrier.

Q: What if my baby develops a rash even with ointment?

A: If the rash looks bright red, bumpy, or won’t go away after a few days of using a thick ointment, call your pediatrician. This might be a yeast infection needing medicated treatment.

Q: Should I choose a cream or a paste?

A: Pastes are thicker and offer stronger protection, ideal for overnight use or treating existing rashes. Creams are lighter and spread more easily for quick changes during the day.